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Broken

"This cabinet displayed a round-bottomed flask that broke during the installation of the exhibition, and which I attempted to mend. The accompanying BWC medicine chest manual highlights the qualities the company wanted to portray as unique to the Tabloid medicine chest and that they believed would set them apart from competitors – such as the longevity of the medicines they sold and the indestructability of the chests (BWC 1925: 2–3). Addressing the supposed indestructability of the chest by focusing specifically on the wide array of glass-stoppered bottles that form a large part of its overall contents and which, according to BWC, ensured the longevity of the medicines, this exhibit displayed a laboratory bottle of similar material, but in a state that demonstrates its fragility. As such, it subverts BWC’s grand claims of indestructability and thereby throws the rest of its claims into doubt" (Liebenberg 2021: 259).
Forest

"The bottles and pipettes in 'Forest' were originally sourced from the storage rooms of the Chemistry department, where they awaited disposal. This cabinet responded to the lacuna of indigenous material represented by the chest and addressed this imbalance by filling the bottles with teas made from local medicinal plants. Staging the bottles and pipettes to simulate a forest references the prejudice of Burroughs, Wellcome and Co (BWC) against these natural remedies, ‘purifying’ them through laboratory processes before they were deemed trustworthy and marketable. This process also occluded the original source of the remedies and sowed the seeds of biopiracy. The various items of glassware in this cabinet were filled with a selection of infusions made from Balotta africana, Sutherlandia frutescens, Agathosma crenulata, Melianthus major, Mentha longifolia, Petroselinum crispum, Hypoxiz villosa and Salvia officinalis" (Liebenberg 2021: 255).
Weighing Smoke

PAUL That’s the man. Well, Raleigh was the person who introduced tobacco in England, and since he was a favourite of the Queen’s – Queen Bess, he used to call her – smoking caught on as a fashion at court. I’m sure Old Bess must have shared a stogie or two with Sir Walter. Once, he made a bet with her that he could measure the weight of smoke. DENNIS You mean, weigh smoke? PAUL Exactly. Weigh smoke. TOMMY You can’t do that. It’s like weighing air. PAUL I admit it’s strange. Almost like weighing someone’s soul. But Sir Walter was a clever guy. First, he took an unsmoked cigar and put it on a balance and weighed it. Then he lit up and smoked the cigar, carefully tapping the ashes into the balance pan. When he was finished, he put the butt into the pan along with the ashes and weighed what was there. Then he subtracted that number from the original weight of the unsmoked cigar. The difference was the weight of the smoke. TOMMY Not bad. That’s the kind of guy we need to take over the Mets. PAUL Oh, he was smart, all right. But not so smart that he didn’t wind up having his head chopped off twenty years later. (Pause) But that’s another story.
The experiment (Wine into water)

An experiment in three parts, reversing the first miracle.
Weighing Air

An example from demonline (UCT Physics Department’s website with descriptions of educational demonstrations). Its descriptions reads: "A spherical flask of about 1 litre is suspended from one arm of a crude chemical balance. It is counterpoised by weights in the other pan, the tap attached to the sphere being open. This gives (roughly) the true weight of the glass. Unhook the sphere from the stirrup, attach the rubber tube from a rotary vacuum pump to the glass tube and evacuate for around 30s. Close tap, and re-attach stirrup. There will now be an upthrust on the flask equal to the weight of air removed, and the weights in the other pan will have to be reduced by about 1.2 g to restore the balance. Open the tap again: the air can be heard rushing into the flask (class must keep quiet), and the flask suddenly descends again".
The Brown Dog Affair (1903 - 1910)

On Feb. 2, 1903, English physicians William Bayliss and Ernest Starling, gave a lecture on the digestive system to a theatre full of medical students. Also in attendance were Lizzy Lind af Hageby and Leisa Schartau, committed feminists and anti-vivisectionists. They had travelled from Sweden to enrol at the London School of Medicine for Women, attend lectures around town, and document the practice of vivisection in British universities. During the lecture, a brown terrier was wheeled out, strapped to a board. Starling had already performed one experiment on the dog two months earlier, shutting off its pancreas. This time, Bayliss cut open the dog’s neck and spent half an hour unsuccessfully trying to stimulate the animal’s salivary glands with electrodes. Eventually, he gave up and handed the dog over to a student (Henry Dale, another future Nobel laureate) who stabbed it through the heart, thus ending the lesson. What followed was a court case filed by Stephen Coleridge, a prominent barrister and secretary of the National Anti-Vivisection Society against Bayliss. After four days of testimony, the judge called the women’s account “hysterical” while giving instructions to the jury. The jurors conferred for 20 minutes, then found Coleridge guilty of libel. Anti-vivisectionists commissioned a bronze statue of the dog as a memorial, unveiled in Battersea in 1906. Its plague, which read "Men and women of England, how long shall these Things be?" led to the it being vandalised on a frequent basis. On 10 December 1907, hundreds of medical students marched through central London waving effigies of the brown dog on sticks, clashing with suffragettes, trade unionists and 300 police officers, one of a series of battles known as the ‘Brown Dog’ riots. In March 1910, tired of the controversy, Battersea Council sent four workers accompanied by 120 police officers to remove the statue under cover of darkness, after which it was reportedly melted down by the council's blacksmith.
Rats laugh when you tickle them

In 1999, Jaak Panksepp and Jeffrey Burgdorf successfully demonstrated that tickling young rats spurs them into letting out the same ultrasonic giggles they make during play.
Coda

Metronome, fishing hook, sinker, crimp and laboratory clamp. The fishing sinker supplies a counter weight, which allows ticking to continue even though the metronome is suspended upside down. The weight is however, exercising a force which will inevitably exhaust the metronome spring, causing it to cease functioning.
About Ed Ricketts

"Just about dusk one day in April 1948 Ed Ricketts stopped work in the laboratory in Cannery Row. He covered his instruments and put away his papers and filing cards. He rolled down the sleeves of his wool shirt and put on the brown coat which was slightly small for him and frayed at the elbows. He wanted a steak for dinner and he knew just the market in New Monterey where he could get a fine one, well hung and tender. He went out into the street that is officially named Ocean View Avenue and is known as Cannery Row. His old car stood at the gutter, a beat-up sedan. The car was tricky and hard to start. He needed a new one but could not afford it at the expense of other things. Ed tinkered away at the primer until the ancient rusty motor coughed and broke into a bronchial chatter which indicated that it was running. Ed meshed the jagged gears and moved away up the street. He turned up the hill where the road crosses the Southern Pacific Railways track. It was almost dark, or rather that kind of mixed light and dark which makes it very difficult to see. Just before the crossing the road takes a sharp climb. Ed shifted to second gear, the noisiest gear, to get up the hill. The sound of his motor and gears blotted out every other sound. A corrugated iron warehouse was on his left, obscuring any sight of the right of way. The Del Monte Express, the evening train from San Francisco, slipped around from behind the warehouse and crashed into the old car. The cow-catcher buckled in the side of the automobile and pushed and ground and mangled it a hundred yards up the track before the train stopped" (Steinbeck 1951: 279). After Ricketts' death in 1948, Steinbeck dropped the species catalogue from the earlier 'The Sea of Cortez' and republished it with a eulogy to his friend added as an afterword.
Kuhn's Jellyfish

Kuhn's "example illustrates how the entrenched expectations of experimental outcomes and prescribed instrumental functions of an insider’s view of the laboratory and its equipment can pose a threat to new discoveries. The circumstances that enabled Roentgen (an insider) to first notice these new rays are not clear, but Kuhn proposes that the occurrence of anomaly enables discovery and that Roentgen’s ‘recognition that nature has somehow violated the paradigm-induced expectations that govern normal science’ (1970: 52–3) was important. Kuhn emphasises that Roentgen valued the anomaly instead of ignoring it – a vital step in the process of discovery" (Liebenberg 2021: 114).
Haematite Miner's Lung (Or Sidero-silicosis)

Catalogue No: R3-d55-0331. Origin: UCT Anat Path museum. Old Museum No: V:x:6. Year: not recorded. Clinical data: No further clinical or laboratory details are available other than that the patient was an emaciated 50 year old man. Macroscopy: The specimens preserved are both lungs, the heart, kidneys, spleen and and portions of liver. In the thorax, both pleural cavities were completely obliterated by a fibrous pleurisy of long-standing and both lungs were universally adherent throughout. They were stripped off with difficulty and were found to have thickening of the pleura over the upper lobe on the left side and the upper and middle lobes on the right. The lower lobes on both sides were soft and spongy while the upper lobes were dense and firm on palpation but on section there was no cavitation and no evidence of tuberculosis. The left lung showed a dense fibrosis of the whole of the upper lobe and the upper third of the lower lobe; no crepitant lung tissue could be found in the upper lobe while the lower two-thirds of the lower was crepitant and showed emphysema of a hypertrophic nature. The lung was a dull brick colour and haematite dust flowed out with the fluid when the lung was sectioned. The right lung presented a similar appearance to the left. There was a solid dense fibrosis of the upper and middle lobes and the lower lobe showed fibrosis with hypertrophic emphysema. There was no evidence of tuberculosis and on palpation, a dense fibrosis was found with no nodular formation whatever. On section, it showed a similar appearance of a brick-dust colour, dilated bronchi and uniform fibrosis of the upper and middle lobes with no crepitant lung tissue. The pericardial sac was slightly increased in size due to a hypertrophied and dilated heart. The hypertrophy was mostly on the right side and there was a terminal dilatation of the right atrium; the valves and coronary vessels unremarkable.The liver was small and on section showed venous congestion and cloudy swelling. Microscopy: On microscopy, sections of lung show a diffuse fibrosis of both upper lobes with no recognizable lung tissue. The fibrosis in areas has a slightly whorled arrangement, the centre of which is hyaline and contains no iron pigment and surrounding it is a zone of cellular tissue containing masses of iron. In the upper part of the lower lobe where the lung tissue is recognizable as such, a few nodules definitely resembling silica nodules are to be seen. In the both lower lobes a solid oedema was noted and emphysema marked. The fibrosis was not present to anything like the same extent in the lower lobes, the emphysema being the most marked feature. No evidence of tuberculosis was found in either lung, though a calcareous gland was found in the hilum. Under polarised light, the iron showed up as a golden brown with a few points of light, clear, needle-like in contra-distinction to the iron lying free in the fibrous tissue. The macrophages are beautifully shown lying inside the alveoli filled with iron dust. Percentage of Ash 16.6 Percentage of silica to ash 6.6 Percentage of silica to dry lung 1.1 Percentage of iron to ash 10.3 Percentage of iron to dry lung 6.7 Comments: In summary, the post mortem findings were of: Dense pulmonary fibrosis; hypertrophied and dilated right ventricle; failure of compensation. This condition is described as haematite miner's lung or sidero-silicosis, caused by the inhalation of dust containing silica and ferric oxide which is the principal component of the ore. The fibrosis is thought to be caused primarily by the silica and the exact role of the iron pigment in the pathogenesis of the lesion is not clear. The earliest lesions occur as small densely fibrous, sub-pleural foci usually in the upper lobes; these grow by coalescence of adjacent foci until a diffuse fibrosis of the whole lobe is produced. Haematite miner's fibrosis is commonly associated with tuberculosis and other chronic lung infections; in addition there is quite a high incidence of carcinoma of the lung reported in these cases.
Tobacco Mosaic Virus

During the late 19th century, tobacco farmers observed a strange occurrence on the leaves of their tobacco plants. A mosaic pattern of light and dark green (or yellow and green, in some instances) appeared on the leaves of their crops, the presence of which signalled the steady decline in the plant’s growth. Because of the lucrative nature of the industry, finding a treatment for this seemingly infectious disease became a priority, with many laboratories working to isolate the cause. Bacteria were recognised as the causative agents of many infectious diseases of plants and animals, including humans, in the second half of the 19th century – and the technique of filtration was developed to separate infectious agents from extracts or exudates in order to study these microbes. It was whilst utilising this technique that Dmitri Ivanovski, a Russian microbiologist working in the Crimea in 1890, made a surprising discovery. Using the Chamberland–filter made from porcelain and designed to trap ordinary bacteria, Ivanovsky discovered that the filtered sap from the diseased plants could continue to transfer the infection to healthy plants – an occurrence he attributed to an agent which must be an exceedingly small parasitic microorganism, invisible even under great magnification. It would take another 45 years before the visualisation of this subcellular entity would be formulated with the help of an electron microscope, but Ivanovksy, along with the Dutch botanist M.W. Beijerinck, who also and independently, isolated these microbes in his laboratory in 1898, are generally credited for the discovery of viruses. The disease which infected the tobacco plants would be aptly called the Tobacco Mosaic Virus, and its identification would signal the initiation of a field of study known as virology.
Holes

A virus attacks a cell by attaching itself to the outer wall. It then uses a specialized protein to digest a small hole in the wall of the cell and inject its nucleic acid molecule into the cell's cytoplasm.